卵巢miRNA研究进展

doi:10.11843/j.issn.0366-6964.2014.04.001

Abstract

Abstract:

Ovaries are the most important reproductive organs in female animals.Understanding the molecular regulatory mechanisms of follicular development and hormone secretion is beneficial to improvement of livestock production，the diagnosis and treatment of human ovarian diseases.The miRNAs are small non-coding RNAs that are approximately 22 nucleotides (nt) in length.The majority of miRNAs are ubiquitous and highly conserved across species.The miRNAs regulate target genes via translational repression or degradation of target mRNA.Many studies indicated that miRNAs play critical roles in almost all ovarian biological processes，including folliculogenesis，follicle development，follicle atresia，luteal development and regression.The comprehensive investigation of ovarian miRNA will help to reveal the molecular mechanisms of ovarian functions post-transcriptionally.Herein，the advance in ovarian miRNA researches in recent years，especially in follicular development and ovarian diseases，are summarized.

CLC Number:

S814

XU Yuan，SUN Tie-cheng，ZHANG Ai-ling，LI Jia-qi. Progress on the Research of Ovarian miRNA[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2014, 45(4): 509-516.

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Progress on the Research of Ovarian miRNA

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